Abstract

ABSTRACT This article examines the complexities of managing recurrent thyroid cancer, advocating for a personalized approach supported by multidisciplinary collaboration, and underlining that surgery is reserved for those with structural recurrence. The American Thyroid Association guidelines now utilize a dynamic risk assessment model that moves beyond traditional staging systems to account for therapeutic responses as part of predicting recurrences, including the significance of serum thyroglobulin (Tg) levels. Illustrative case studies underscore the importance of thorough preoperative evaluation and planning with imaging and Tg measurements. The use of intraoperative technology, such as nerve monitoring and parathyroid autofluorescence can also assist in better surgical outcomes. Ultimately, a collaborative approach within a thyroid-specific tumor board is presented as essential for optimizing patient care in complex thyroid cancer cases.

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